Hypothalamic aging datasets
Compare hypothalamic aging RNA-seq studies in mouse, rat and rhesus macaque, with age ranges, assay differences and links to the available datasets.
8 selected datasets · Comparison guidance and source links
Choose a research question
Hypothalamus research guides
Choose a guide for your research question. Each guide compares species, sampled regions, experimental groups and RNA preparations, with links to the studies available in HypoExplorer.
The guides cover selected studies within the larger library. A dataset can appear in more than one guide when it addresses both questions, such as a single-cell study of fasting. Inclusion depends on the comparison available here, rather than every topic discussed in the source paper.
Wenyuan He created HypoExplorer and holds a PhD from the University of Toronto. About the author.
Hypothalamus datasets for obesity and diet research
Find hypothalamus datasets for high-fat diet, obesity and leptin deficiency. Compare dietary controls, brain regions and cell preparations.
9 selected datasets · Comparison guidance and source links
Hypothalamic fasting and feeding datasets
Find fed-versus-fasted hypothalamus datasets, AGRP and POMC neuron studies, dietary restriction and timed feeding. Check each comparison and assay.
10 selected datasets · Comparison guidance and source links
Single-cell and single-nucleus hypothalamus datasets
Browse hypothalamus scRNA-seq and snRNA-seq data. The macaque atlas has population tracks; the mouse studies use animal pseudobulk.
7 selected datasets · Comparison guidance and source links
Know an accession or paper already?
The complete study directory lists every dataset available in the explorer with its GEO or other repository accession and source publication where available. Use a guide to understand study differences, or go directly to a study when you already know the source.
The Methods page explains how source data and comparisons are represented. About HypoExplorer identifies the app author and provides a contact for corrections.