Pig hypothalamus — Iberian genotype
Sus scrofa · Whole hypothalamus · bulk RNA-seq
Selected data and study scope
This dataset contains bulk RNA-seq data from Sus scrofa, sampled from whole hypothalamus. The default comparison examines gene expression in Pure Iberian relative to Iberian × Large White.
The explorer includes 1 track and 1 comparison for this dataset.
The default track, Whole hypothalamus, includes 10 Iberian × Large White samples and 10 Pure Iberian samples in this comparison. These are analysis sample counts. Check the source for biological replication and pooling.
Interpretation and limitations
The measurement combines expression from the cells in the tissue sample. A difference in tissue expression alone does not identify which cell type contributes to it.
Expression values use log2(author-normalized expression + 1). Keep this unit when exporting or comparing values. Values on other normalization scales are not directly interchangeable.
Evidence and verification
Pipeline QC review needed. Pig hypothalamus — Iberian genotype; all 1 registered contrasts on default track hypothalamus
Experimental design review needed. Pig hypothalamus — Iberian genotype; all 1 registered contrasts on default track hypothalamus
Author concordance review needed. Selected author genes only; iberian_vs_crossbred_sex_adjusted. P values and FDR are contextual. Numerical acceptance: strong correlation and matched-gene direction.
Pipeline QC can pass while experimental-design limitations remain. Read both assessments before interpreting results.
Open the dataset in the Explorer to read each check and its evidence. Author concordance compares effects for matched genes. It does not require identical author P values or FDR.
Read the analysis methods and interpretation guide and how to cite the source study and HypoExplorer. The source publication may include tissues, groups or comparisons beyond the data shown here.
Source study
Whole-hypothalamus RNA-seq comparing ten pure Iberian with ten Iberian × Large White pigs at two months, balanced five female and five male per genotype and adjusted for sex. GEO-described normalized expression is transformed as log2(x+1); five HTSeq summary rows are quarantined and no integer-looking values are reinterpreted as raw counts (GSE201408)
Repository study title
Hypothalamic transcriptome in pure (Iberian x Iberian) and crossbred (Iberian x Large White) pigs at 2 months old
The original study authors produced these data. HypoExplorer displays selected data and analyses that may cover only part of the study.
Comparisons in HypoExplorer
Pure Iberian vs Iberian × Large White · default
Positive differential-expression values indicate higher expression in the case group relative to the baseline. Check the comparison direction and study design when interpreting results.
Available tracks
| Track | Features | Iberian × Large White n | Pure Iberian n |
|---|---|---|---|
| Whole hypothalamus | 14,306 | 10 | 10 |
Expression and analysis results
Open this dataset to inspect gene expression and differential-expression results across the available tracks. Pathway enrichment is also available. The pathway databases differ by dataset.
HypoExplorer is in beta testing. Features and analyses may change during testing. Review the original source, analysis methods and quality-control checks before using a result in research.